2E: Sex, Ancestral & Geographical Determinants in Biomaterials Research

Timeslot: Wednesday, April 19, 2023 - 2:45pm to 4:15pm
Room: Coral 3-4

About

The unprecedented nature of the COVID-19 pandemic has reintroduced/continued the conversation about the health inequities that disproportionately affect individuals based on social determinants of health like gender, race, and socioeconomic background. From an engineering and scientific perspective, biological sex and genetic ancestral differences can be used to shed light on differences between patient populations, as these variables have been shown to result in differences in both disease prevalence and manifestation. Yet, our mechanistic knowledge of the underlying molecular and cellular mechanisms involved, and how these differences lead to performance differences for biomaterials, remain poorly characterized. This session will showcase the current status and future of purposefully designed biomaterials to address both health and healthcare disparities and study their underlying causes. This session will encompass a diverse portfolio of topics including (but not limited to) the design of sex- and ancestry- specific cellular microenvironments, the development of sex-specific drug delivery approaches, and the fabrication of biomaterials to address challenges in global health.

  • 2:45 PM 71. Metanalysis of Global Participation in Biomaterials Publications. Ana Porras, University of Florida.

  • 3:00 PM. 72. Leveraging Machine Learning to Assess How Ancestry is Reported in Biomaterial Models. Nisha Kotta, Alison Veintimilla, Tomer Zilbershtein, Ylan Beaudoin de Roca, Dr. Erika Moore. University of Florida, Thomas Jefferson University.

  • 3:15 PM 73. Omniphobic Spray Coating Created from Hierarchical Structures with Repel and Kill Mechanism Prevents the Pathogenic Contamination of High-touch Surfaces. Noor Abu Jarad, Kenneth Rachwalski, Fereshteh Bayat, Shadman Khan, Amid Shakeri, Roderick MacLachlan, Martin Villegas, Prof. Tohid Didar. McMaster, McMaster University.

  • 3:30 PM 74. Circulating Sex Hormone Response to Traumatic Brain Injury: Implications for Drug Delivery. Amberlyn Simmons, Veronica Pena, Heather Bimonte-Nelson, Dr. Chris Plaisier, Dr. Sarah Stabenfeldt, Dr. Rachael Sirianni. Arizona State University, University of Massachusetts Amherst.

  • 3:45 PM 75. Sex-specific Valvular Myofibroblast Activation in Response to Nano-scale Stiffness Cues. Rayyan Gorashi, MS; Michaela Wenning, BS; Joseph Grim, PhD; Cierra Walker, PhD; Brisa Pena, PhD; Luisa Mestoni, PhD; Kristi Anseth, PhD; Brian Aguado, PhD; University of California, San Diego, University of Colorado, Boulder, University of Colorado, Anschutz Medical Campus, Sanford Consortium for Regenerative Medicine.

  • 4:00 PM 76. A Cell-Degradable, Photo-Stiffening Hydrogel to Study Sex-Differences in Pulmonary Fibrosis. Mikala Mueller, MS; Chelsea Magin, PhD. University of Colorado Denver , Anschutz Medical Campus