2F: Extracellular Vesicles for Biomedical Applications

Timeslot: Wednesday, April 19, 2023 - 2:45pm to 4:15pm
Room: Coral 5

About

Extracellular vesicles (EVs) are natural nanoparticles that carry RNA, DNA, proteins, and lipids, and have been given much attention in recent years due to the growing knowledge of their role in driving disease and maintaining health. The objective of this session entitled " Extracellular Vesicles for Biomedical Applications" is to bring together investigators focusing on the characterization and biology of EVs, engineering of EVs, and their utility as diagnostic biomarkers and therapeutics. Example topics include EV nanomaterials science, the interaction of EVs with biological systems, EV biodistribution in vivo and pharmacology, and the utility of EVs for molecular targeting, imaging, diagnostics, tissue engineering, and drug delivery. This session will target scientists from a wide background (graduate students, postdoctoral fellows, academic professors, industry members, clinicians) who are developing EVs towards biomedical applications.

  • 2:45 PM 77. Stem Cell-Derived Exosome Nebulization Therapy (SCENT) Promotes Heart Repair in Mice and Pigs. Junlang Li, Dr. Ke Cheng. University of North Carolina at Chapel Hill & North Carolina State University.

  • 3:00 PM 78.Engineered Extracellular Vesicles Attenuate Inflammation in a Murine Model of Acute Lung Injury. Ana Salazar Puerta, Maria Rincon Benavides, Tatiana Cuellar-Gaviria, Lilibeth Ortega-Pineda, Devleena Das, Daniel Dodd, Daniel Gallego-Perez, Natalia Higuita-Castro. The Ohio State University.

  • 3:15 PM 79. Phosphatidylserine-incorporated Exosome Mimetics Encapsulating CXCR3 Antagonist Inhibit Osteoclast Differentiation and Alleviate Osteoporosis. Minjee Kang, PhD; Jiabing Fan, M.D..PhD; Michelle Chiang, Tara Aghaloo, DDS, PhD; Min Lee, PhD. University of California, Los Angeles, University of Maryland Eastern Shore.

  • 3:30 PM 80. Engineered Extracellular Vesicles Loaded with Pro-Vascular Cargo Induced Direct Reprograming to Endothelial Cells and Promote Wound Closure In Vivo. Maria Rincon-Benavides, Dr. Tatiana Cuellar-Gaviria, Natalia Mendonca, Ana Salazar-Puerta, Dr. Britani Blackstone, Dr. Heather Powell, Dr. Daniel Gallego-Perez, Dr. Natalia Higuita-Castro. The Ohio State University.

  • 3:45 PM 81. Immune Engineered Extracellular Vesicles to Modulate T Cell Activation in Type 1 Diabetes. Matthew Becker, PhD; Leeana Peters, Thinzar Myint, PhD; Todd Brusko, PhD; Edward Phelps, PhD. University of Florida.

  • 4:00 PM 82. Analysis and Biomimetic in vitro Modeling of Extracellular Vesicle-Mediated Perineural Invasion. Emory Gregory, Isabel Powers, Azemat Jamshidi-Parsian, MS; Robert Griffin, PhD; Young Hye Song, PhD; University of Arkansas, University of Arkansas for Medical Sciences.