3D: Biomaterials for Organoids
Timeslot: Thursday, April 20, 2023 - 10:30am to 12:00pm
Room: Coral 1-2
About
An organoid is a self-organized three-dimensional tissue that is typically derived from stem cells (pluripotent, fetal or adult) and which mimics the critical functional, structural, and biological complexity of an organ, such as the gut, brain, eye, pancreas, liver, kidney, and lung. Organoids bridge a gap in existing model systems by providing a more stable system amenable to extended cultivation and manipulation while more representative of in vivo physiology. This session will cover the most recent advancements of biomaterials-mediated organoid and organ chip technologies in regenerative medicine, cancer therapy, drug testing, environmental control, monitoring, adaptive sensing, and translational applications. This topic was well-received in the previous SFB meetings and is an exciting emerging research area. In 2023, we will continue this session and promote the translational impacts of biomaterials-mediated organoid projects.
10:30 AM. 110. Induced Epithelial Curvature in Photopatterned Intestinal Organoids Regulates Symmetry Breaking via Pre-Transcriptional Changes in Membrane Tension and Resting Potential. Bruce Kirkpatrick, Francis Yavitt, Radu Moldovan, PhD; Peter Dempsey, PhD; Kristi Anseth, PhD. University of Colorado Medical Scientist Training Program, University of Colorado Boulder Department of Chemical and Biological Engineering, BioFrontiers Institute, University of Colorado Anschutz Advanced Light Microscopy Core, University of Colorado Anschutz Department of Pediatrics.
10:45 AM. 111. Study Transportation of Drugs within Newly Established Colon Organoid Systems. Qun Wang, Dr. Zahra Davoudi. Iowa State University.
11:00 AM. 112. Pancreatic Differentiation of iPSC in Thiol-Norbornene Photo-Click Hydrogels. Chien-Chi Lin, PhD; Matthew Arkenberg. Purdue University.
11:15 AM. 113. Spatially Controlled Fabrication of Assembloids with 3D Bioprinting. Michelle Huang, Julien Roth, Lucia Brunel, Yueming Liu, Betty Cai, Sauradeep Sinha, Fan Yang, PhD, Sergiu Pasca, MD, Sungchul Shin, PhD, Sarah Heilshorn, PhD. Stanford University.
11:30 AM. 114. Rapid and Facile Light-Based Approach to Generate Gut-On-A-Chip Systems Asing Synthetic Hydrogels. Ana Mora-Boza, PhD, Adriana Mulero-Russe, Ankur Singh, Andrés J. García. Georgia Institute of Technology.
11:45 AM. 115. Engineering Human Induced Pluripotent Stem Cell Derived Neural Tissue Constructs for Modeling Neuroinflammation and Neurotoxicity. Joydeb Majumder, PhD, Elizabeth Torr, William L. Murphy, PhD. University of Wisconsin-Madison.