5D: Stimuli-Responsive Biomaterials

Timeslot: Thursday, April 20, 2023 - 3:45pm to 5:45pm
Room: Coral 1-2

About

Materials that respond to environmental stimuli, such as heat, light, pH, or biological signals, provide unique tools for environmentally-responsive and/or temporal changes in biomaterial properties over time. These materials have broad potential applications in drug delivery, cell-responsive materials, tissue engineering, and medical device implantation. This session will highlight recent advances in designing and characterizing stimulus-responsive biomaterials.

  • 3:45:00 PM 225. Dithiolane-Based Dynamic Hydrogels for Photoinduced Crosslinking, Exchange, and Depolymerization. Benjamin Nelson, Bruce Kirkpatrick, Connor Miksch, Matthew Davidson, PhD, Nathaniel Skillin, Grace Hach, Benjamin Fairbanks, PhD, Jason Burdick, PhD, Christopher Bowman, PhD, Kristi Anseth, PhD, University of Colorado Boulder, Boulder, CO, USA.

  • 4:00 PM 226. Developing Enzyme-Sensitive Peptide-Polymer Conjugates for Cell-Mediated Degradation. Natasha Hunt, Srujan Singh, M.Tech, E. Thomas Pashuck, PhD, Warren Grayson, PhD, Lesley Chow, PhD, Lehigh University, Bethlehem, PA, USA, Johns Hopkins University, Baltimore, MD, USA.

  • 4:15 PM 227. Bioactive Protein Photorelease from Hydrogels via Tissue-penetrating Green Light. Teresa Rapp, PhD, Cole DeForest, PhD, University of Washington, Seattle, WA, USA.

  • 4:30 PM 228. Sorting and Harvesting Cells With Dynamic Bionterfaces. Sergiy Minko, PhD, Yongwook Kim, Ummay Jahan, Alexander Delchev, Nickolay Lavrik, Vladimir Reukov, University of Georgia, Athens, GA, USA, Oak Ridge National Lab, Oak Ridge, TN, USA.

  • 4:45 PM 229. Ultrasound-Responsive Biomaterial Platform for 3D Spheroid Gene Delivery to Model Early Tumor Initiation. Katherine Huynh, B.S., Mary Lowrey, B.S., Sara Evans-Dutson, B.S., Kevin Schilling, PhD, Danielle Brasino, PhD, Mithila Handu, PhD, Sean Speese, PhD, Carolyn Schutt Ibsen, PhD, Oregon Health and Science University, Portland, OR, USA.

  • 5:00 PM 230. A Protease-Based Theranostic as a Tool to Understand and Inhibit Calpain in Brain Injury. Marianne Madias, BS, Sophia Warlof, Ester Kwon, PhD, BS, University of California, San Diego, La Jolla, CA, USA.

  • 5:15 PM 231. Novel Intrinsically Disordered Protein Polymers with Tunable Band-Pass Phase Separation Behavior. Maria Giraldo Castano, Felipe Garcia Quiroz, Emory University, Atlanta, GA, USA, Georgia Institute of Technology, Atlanta, GA, USA.

  • 5:30 PM 232. Matrix Remodeling Modulates Therapeutic Potential of Heterotypic Cell Spheroids for Wound Healing. Victoria Thai, David Ramos-Rodriguez, PhD, Jonathan Leach, PhD, University of California Davis, Davis, CA, USA.