5E: Engineering Cells & Their Microenvironments (SIG) 1
Timeslot: Thursday, April 20, 2023 - 3:45pm to 5:45pm
Room: Coral 3-4
About
The Engineering Cells & Their Microenvironments Special Interest Group concentrates on technologies and approaches focused at the single cell level and encompassing engineering cell microenvironments, biomaterial-induced cell signaling, stem cell manufacturing and differentiation, immunoengineering, and biomaterials for cell-based detection and diagnosis.
3:45 PM 233. Poly(Ethylene Glycol)-Based Microcarriers Alter Secretory Activity of Genetically-Modified Mesenchymal Stromal Cells. Gilad Doron, PhD, Levi Wood, PhD, Robert Guldberg, PhD, Johnna Temenoff, PhD, Georgia Institute of Technology & Emory University, Atlanta, GA, USA, University of Oregon, Eugene, OR, USA.
4:00 PM 234. Strain-Stiffening Bottlebrush Polymer Hydrogels Influence hMSC Morphology and Mechano-transduction. Monica Ohnsorg, Varsha Rao, Alex Khang, Kristi Anseth, University of Colorado Boulder, Boulder, CO, USA.
4:15 PM 235.Stem Cells in Sliding Hydrogels ‘Dance’ to Enhance 3D Chondrogenesis via Early Cytoskeletal and Nuclear Dynamics. Manish Ayushman, Georgios Mikos, Xinming Tong, Pamela Cai, Andrew Spakowitz, Sarah Heilshorn, Fan Yang, Stanford University, Stanford, CA, USA.
4:30 PM 236. Stiff and Fast-Relaxing Hydrogel to Probe Pancreatic Ductal Adenocarcinoma Cell Behavior. Han Nguyen, Chien-Chi Lin, PhD, Purdue University, West Lafayette, IN, USA, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.
4:45 PM 237. Extracellular Matrix Stiffness Mediates Insulin Secretion in Pancreatic Islets via Phosphofructokinase Activity. Chelsea Garcia, BS, Keifer Holcomb, BS, Nikki Farnsworth, PhD, Colorado School of Mines, Golden, CO, USA.
5:00 PM 238. Enzyme-Functionalized Covalent Alginate Microparticles for Low-Cost Anaerobic Culture. Tyrell Williams, Claudia Daboin, Paul Kim, Fengguang Guo, Paul de Figueiredo, PhD, Daniel Alge, PhD, Texas A&M University, College Station, TX, USA.
5:15 PM 239. Preserving Vasculature on the Encapsulation Device Led to Successful Stem Cell Derived Beta Cell Engraftment. Gauree Chendke, Bhushan Kharbikar, PhD, Sudipta Ashe, PhD, Matthias Hebrok, PhD, Tejal Desai, PhD, University of California San Francisco, San Francisco, CA, USA, Technical University Munich (TUM), Garching-Forschungszentrum, Germany, Institute for Diabetes and Organoid Technology (IDOT) and Helmholtz Diabetes Center (HDC), Neuherberg, Germany, Brown University, Providence, RI, USA.
5:30 PM 240. Non-Specific Proteolytic Degradation of Peptides Within Hydrogels Impacts Cell Function. Samuel Rozans, MS, Eugene Pashuk, PhD, Lehigh University, Bethlehem, PA, USA.