7B: Biomaterial-Based Vitro Cancer/Tumor Models for Drug Screening and Diagnostics 1
Timeslot: Friday, April 21, 2023 - 2:00pm to 3:30pm
Room: Silver Pearl 2
About
Biomaterial-based in vitro cancer/tumor models offer a close mimic of the complex tumor microenvironment, providing versatile platforms for drug and toxicology screening as well as diagnostics. The implementation of these preclinical tools can afford low-cost, easy-to-use systems to evaluate cancer treatments, enhancing the efficacy and toxicological assessment for specific patients, mitigating the limitations of current technologies, and expanding the treatment options and patient’s quality of life.
2:00 PM. 347. INVITED SPEAKER
2:30 PM 348. Adhesion Strength of Disseminating Tumor Cells Predicts Severity of Metastatic Disease. Katherine Birmingham, PhD, Benjamin Yeoman, PhD, Madison Kane, Pranjali Beri, PhD, Jeremy Tuler, Isabelle Williams, Aditya Kumar, PhD, Sarah Klein, Parag Katira, PhD, Adam Engler, PhD, University of California, San Diego, San Diego, CA, USA, San Diego State University, San Diego, CA, USA, Genomics Institute of the Novartis Foundation, San Diego, CA, USA, Moores Cancer Center, San Diego, CA, USA, Sanford Consortium for Regenerative Medicine, San Diego, CA, USA.
2:45 PM 349. Gold-Coated Microfluidic-Based Enhanced Capture, Controlled Release, and In Vitro Culture of Heterogeneous Circulating Tumor Cells. Elyahb Allie Kwizera, PhD, Xiaoming He, PhD, Katherine Tkaczuk, MD, University of Maryland Baltimore, Baltimore, MD, USA.
3:00 PM 350. A Versatile, Reductionist Platform for Studying 3D Microenvironmental Interactions in Colorectal Cancer. Irina Kopyeva, Ross Bretherton, Jessica Ayers, Ming Yu, William Grady, Cole DeForest, PhD, University of Washington, Seattle, WA, USA, Fred Hutchinson Cancer Center, Seattle, WA, USA.
3:15 PM 351. Tuning Mineral Cues Modulates Breast Cancer-Bone Metastasis in a Spatially Patterned 3D Model. Michelle Tai, Eva González Díaz, PhD, Angelina Mao, Fan Yang, PhD, Stanford University, Palo Alto, CA, USA.