10:15 AM. 430. INVITED SPEAKER .

10:45 AM 431. Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta During Pregnancy. Kelsey Swingle, Michael Mitchell, PhD, University of Pennsylvania, Philadelphia, PA, USA.

11:00 AM 432. Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease. Rohan Palanki, Sourav Bose, Apeksha Dave, Brandon White, Kelsey Swingle, Margaret Billingsley, William Peranteau, Michael Mitchell, University of Pennsylvania, Philadelphia, PA, USA, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

11:15 AM 433. Delivery of Decorin via Microspheres to Inhibit Fibrosis in Pediatric Vocal Folds. Ryan Friedman, Elizabeth Brown, Matthew Aronson, Karen Zur, MD, Riccardo Gottardi, PhD, University of Pennsylvania, Philadelphia, PA, USA, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

11:30 AM 434. Antimicrobial Peptide Eluting Endotracheal Tubes Prevent Subglottic Stenosis in a Mouse Model. Matthew Aronson, Amrita Mehta, Ryan Friedman, Daniel Ghaderi, Ryan Borek, MD, Hoang Nguyen, MD, PhD, Kendra McDaid, Natasha Mirza, MD, Ian Jacobs, MD, Riccardo Gottardi, PhD, University of Pennsylvania, Philadelphia, PA, USA, Children's Hospital of Philadelphia, Philadelphia, PA, USA, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA.

11:45 AM 435. Development of a Geometrically Tunable Blood Shunt for Pediatric Heart Reconstruction Surgery. Victor Mishin, Shreya Soni, Akari Seiner, Amy Throckmorton, Christopher Rodell, Drexel University, Philadelphia, PA, USA.

12:00 PM 436. Pediatric Gummy Formulations for Drug Resistant Tuberculosis. Kelsey Broderick, Morteza Mostashari, Melissa Wright, Nikolai Braun, PhD, Lindsay Woodard, PhD, Luna Labs USA, Charlottesville, VA, USA.